Dr. Johnathan Storlie

-Genomics, Transcriptomics, and Proteomics of Human Disease
-Recombinant DNA technology
-Human Virology
-MHC Matching and Regenerative Therapy
-Pluripotency and Cellular Differentiation
 
"I want my students to study 'the greats', but not so that they can merely repeat what 'the greats' did in the same mediums. That would only make my students great imitators. My goal is to nurture great innovators. I want students to discover their own poetic spirit and apply it to the new mediums that have only become available to our age. By writing great books and great music, Goethe and Beethoven helped make life richer. By identifying treatments or cures for heritable or infectious diseases, my students will also be able to make life richer for people."-Johnathan Storlie
 
Welcome to Dr. Johnathan Storlie's website. John is the Genetic Genealogist of Giants of the Earth Heritage Center in Spring Grove, MN--a non-profit organization that uses genomics to trace ancestry, find relatives, and merge large family trees. John has also taught Genetics at Luther College and Viterbo Univerity. John is a 1993 graduate of Luther College, where his majors were Political Science and Philosophy. John studied at the University of Muenster (Germany) after graduating from Luther. He earned an MA in Philosophy at Boston College in 1997, studying phenomenology, epistemology, and ethics. John became increasingly interested in biology and earned a BS in Microbiology at the University of Iowa in 2001. He completed his PhD in Microbiology at the University of Iowa, with a specialty in human virology. John was the first researcher to draw a connection between pathogenic varicella-zoster virus gene expression and the activity of certain host HOX transcription factors that regulate cell differentiation. This insight is currently being applied to increase vaccine effectiveness. His research has appeared in the Journal of Medical Virology, Journal of Virology, Microbiology and Molecular Biology Reviews, Journal of Infectious Disease, and Virology journal.
 
John is particularly known for his extremely high magnification 3D micrographs of virally infected cells. In the images at right, viral proteins have been immunofluorescently labeled in infected human cells. Viral major capsid protein is labeled red, glycoprotein E is labeled in blue, and glycoprotein C is labeled green. These viruses are less than 0.5 um in diameter. In Figure A, a cell with two nuclei can be seen. In B, the viral capsids/partially assembled capsids appear red. Using the correct display, these can be viewed as rotatable 3 dimensional images, because they were captured using a confocal microscopy to produce a Z-stack, which is like a series of ultra thin slices of the infected cells from top to bottom that can be reassembled in 3d.    
 
 John and his wife Patty have an eight year old daughter named Elyse, a three year old named Ole Hans, and a baby named Celia. Celia likes dolls, Ole likes Cars II, and Elyse says she wants to be an animal scientist some day, but she is also considering teaching, farming, or being a veterinarian. All three have especially treasured the beautiful handmade baby blankets received from Lynn Williams and Ruth Reitan.

Patty also received her PhD in Microbiology and is currently teaching Physiology, Microbiology, and General Biology to nursing students in Winona, MN. She is from south of Des Moines, originally. Patty grew up helping run her parents' apple orchard. She is a master baker, cook, and gardener. John is originally from a farm in the Spring Grove area. In addition to the 8 hours a day he loves to work analyzing the human genome, he has outside interests in philosophy, biblical hermeneutics, film editing, predatory animal photography/videography (coyotes, wolves, mountain lions), trail running, organic farming, sustainable land use, and genealogy and oral histories.
 
Please feel free to consult John is you have questions related to regenerative therapy, virology, human genetics, bioinformatics, gene therapy, genetic epidemiology, developmental genetics (HOX-related factors), stem cell differentiation, worldwide collaborative stem cell matching, adjuvant-free vaccines, polyglutamine diseases, animal cloning, in vitro fertilization, genetic genealogy, or genetic preservation of rare species.

Contact Johnathan Storlie:

storjo01@luther.edu or john@storlie.org


 



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